Three Mount Sinai orthopedic surgeons have published a guide for managing children and adults with Down syndrome, covering the range of musculoskeletal conditions these individuals experience along with other medical issues that orthopedists should keep in mind when evaluating them.
Down syndrome is the most frequent chromosomal abnormality in Americans, affecting about 1 in 700 babies born in the United States. Their distinct physical features include flattened facial profiles, short stature, and epicanthal folds. Common associated medical conditions include congenital heart disease, thyroid disease, vision problems, and leukemia, along with a range of musculoskeletal complications resulting from generalized ligamentous laxity.
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