An App-Based Game to Treat Depression

Dr. Charney and Dr. Iacoviello have developed an app-based game to treat depression that targets the parts of the brain associated with emotional processing and cognitive control. Players are shown a human face and asked to identify which emotion is shown on the face; over time, this is intended to change the brain circuits associated with depression, significantly reducing symptoms. The concept shows a lot of promise—an early study showed that patients using the app had significantly fewer symptoms of major depressive disorder compared to a control group.

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Dennis Charney, MD.

Dennis Charney, MD

Dennis S. Charney, MD, is Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai and President for Academic Affairs for the Mount Sinai Health System.  He is also a world expert in the neurobiology and treatment of ...

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Brian Iacoviello, PhD.

Brian Iacoviello, PhD

Dr. Iacoviello's research focuses on the patterns of thinking and behavior that underlie depression, bipolar disorder and anxiety disorders such as PTSD, social anxiety and OCD.  Specifically, he is interested in understanding the role ...

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