Newly discovered autoimmune disease associated with testicular cancer

Sean J. Pittock, M.D., an autoimmune neurologist at Mayo Clinic, discusses a newly discovered autoimmune disease that appears to affect men with testicular cancer. Called testicular cancer-associated paraneoplastic encephalitis, the disease causes severe neurological symptoms in men. They progressively lose control of their limbs, eye movements and, in some cases, speech. The disease begins with a testicular tumor, which appears to cause the immune system to attack the brain. Affected men often find themselves misdiagnosed or undiagnosed and appropriate treatment is delayed.

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Sean Pittock, MD.

Sean Pittock, MD

Sean J. Pittock, M.D., is the director of Mayo Clinic's Center for Multiple Sclerosis and Autoimmune Neurology and of Mayo's Neuroimmunology Research Laboratory. Dr. Pittock's clinical and laboratory expertise lies in modifying, for clinical ...

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Divyanshu Dubey, MBBS.

Divyanshu Dubey, MBBS

Divyanshu (Div) Dubey, M.B.B.S., studies central and peripheral autoimmune neurological conditions. This includes searching for novel biomarkers in serum and cerebrospinal fluids of patients with autoimmune and paraneoplastic neurological ...

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